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Eschenmoser coupling reactions starting from primary thioamides. When do they work and when not?

Reactions of thiobenzamide or thioacetamide with 4-bromo-1,1-dimethyl-1,4-dihydroisoquinoline-3(2H)-one, 4-bromoisoquinoline-1,3(2H,4H)-dione and two α-bromo(phenyl)acetamides were examined under various conditions (base, solvent, thiophile, temperature) and structure/medium features that influence...

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Detalles Bibliográficos
Autores principales: Marek, Lukáš, Váňa, Jiří, Svoboda, Jan, Hanusek, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280059/
https://www.ncbi.nlm.nih.gov/pubmed/37346496
http://dx.doi.org/10.3762/bjoc.19.61