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Facile access to 3-sulfonylquinolines via Knoevenagel condensation/aza-Wittig reaction cascade involving ortho-azidobenzaldehydes and β-ketosulfonamides and sulfones

Quinoline-based sulfonyl derivatives, and especially sulfonamides, are relevant and promising structures for drug design. We have developed a new convenient protocol for the synthesis of 3-sulfonyl-substituted quinolines (sulfonamides and sulfones). The approach is based on a Knoevenagel condensatio...

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Detalles Bibliográficos
Autores principales: Malkova, Ksenia, Bubyrev, Andrey, Kalinin, Stanislav, Dar’in, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280061/
https://www.ncbi.nlm.nih.gov/pubmed/37346493
http://dx.doi.org/10.3762/bjoc.19.60

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