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Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2

One of the major cellular mechanisms to ensure cellular protein homeostasis is the endoplasmic reticulum (ER) stress response. This pathway is triggered by accumulation of misfolded proteins in the ER lumen. The ER stress response is also activated in the premature aging disease Hutchinson-Gilford p...

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Detalles Bibliográficos
Autores principales:	Vidak, Sandra, Serebryannyy, Leonid A., Pegoraro, Gianluca, Misteli, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280311/ https://www.ncbi.nlm.nih.gov/pubmed/37210724 http://dx.doi.org/10.1016/j.celrep.2023.112534

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