TIMELESS upregulates PD-L1 expression and exerts an immunosuppressive role in breast cancer

BACKGROUND: Upregulation of the PD-L1 (CD274) immune checkpoint ligand on the tumor surface facilitates tumor immune escape and limits the application of immunotherapy in various cancers, including breast cancer. However, the mechanisms underlying high PD-L1 levels in cancers are still poorly unders...

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Detalles Bibliográficos
Autores principales: Dong, Xinrui, Dai, Huijuan, Lin, Yanping, Sheng, Xiaonan, Li, Ye, Wang, Yaohui, Zhang, Xueli, Jiang, Shuheng, Yin, Wenjin, Lu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280842/
https://www.ncbi.nlm.nih.gov/pubmed/37340461
http://dx.doi.org/10.1186/s12967-023-04257-6

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