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Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

BACKGROUND: Articular injection of mesenchymal stem cells (MSCs) has been applied to treat knee osteoarthritis (kOA), but its clinical outcomes are controversial. This study investigated whether an articular inflammatory microenvironment (AIM) impacts MSC-based therapy in a rat model of kOA. METHODS...

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Detalles Bibliográficos
Autores principales:	Fan, Mengqiang, Tong, Peijian, Yan, Li, Li, Ting, Ren, Jiadan, Huang, Jiefeng, Du, Wenxi, Zhou, Li, Shan, Letian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280917/ https://www.ncbi.nlm.nih.gov/pubmed/37337188 http://dx.doi.org/10.1186/s12916-023-02923-6

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