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The Potential of Artemisinins as Novel Treatment for Thyroid Eye Disease by Inhibiting Adipogenesis in Orbital Fibroblasts

PURPOSE: Thyroid eye disease (TED) causes cosmetic defect and even threatens eyesight due to tissue remodeling in which orbital fibroblast (OF) plays a central role mainly by differentiating into adipocytes. Repurposing old drugs to novel applications is of particular interest. Here, we aimed to eva...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Cheng, Yanglei, Li, Hai, Guan, Hongyu, Xiao, Haipeng, Li, Yanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281061/
https://www.ncbi.nlm.nih.gov/pubmed/37326592
http://dx.doi.org/10.1167/iovs.64.7.28