A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids

The broad research use of organoids from high-grade serous ovarian cancer (HGSC) has been hampered by low culture success rates and limited availability of fresh tumor material. Here, we describe a method for generation and long-term expansion of HGSC organoids with efficacy markedly improved over p...

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Detalles Bibliográficos
Autores principales: Senkowski, Wojciech, Gall-Mas, Laura, Falco, Matías Marín, Li, Yilin, Lavikka, Kari, Kriegbaum, Mette C., Oikkonen, Jaana, Bulanova, Daria, Pietras, Elin J., Voßgröne, Karolin, Chen, Yan-Jun, Erkan, Erdogan Pekcan, Dai, Jun, Lundgren, Anastasia, Grønning Høg, Mia Kristine, Larsen, Ida Marie, Lamminen, Tarja, Kaipio, Katja, Huvila, Jutta, Virtanen, Anni, Engelholm, Lars, Christiansen, Pernille, Santoni-Rugiu, Eric, Huhtinen, Kaisa, Carpén, Olli, Hynninen, Johanna, Hautaniemi, Sampsa, Vähärautio, Anna, Wennerberg, Krister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281085/
https://www.ncbi.nlm.nih.gov/pubmed/37148882
http://dx.doi.org/10.1016/j.devcel.2023.04.012

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