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Transgenerational sperm DMRs escape DNA methylation erasure during embryonic development and epigenetic inheritance

Germline transmission of epigenetic information is a critical component of epigenetic inheritance. Previous studies have suggested that an erasure of DNA methylation is required to develop stem cells in the morula embryo. An exception involves imprinted genes that escape this DNA methylation erasure...

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Detalles Bibliográficos
Autores principales: Ben Maamar, Millissia, Wang, Yue, Nilsson, Eric E, Beck, Daniel, Yan, Wei, Skinner, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281242/
https://www.ncbi.nlm.nih.gov/pubmed/37346491
http://dx.doi.org/10.1093/eep/dvad003