Maternal Embryonic Leucine Zipper Kinase is Associated with Metastasis in Triple-negative Breast Cancer

Triple-negative breast cancer (TNBC) has high relapse and metastasis rates and a high proportion of cancer stem-like cells (CSC), which possess self-renewal and tumor initiation capacity. MELK (maternal embryonic leucine zipper kinase), a protein kinase of the Snf1/AMPK kinase family, is known to pr...

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Detalles Bibliográficos
Autores principales: Xie, Xuemei, Chauhan, Gaurav B., Edupuganti, Ramakrishna, Kogawa, Takahiro, Park, Jihyun, Tacam, Moises, Tan, Alex W., Mughees, Mohd, Vidhu, Fnu, Liu, Diane D., Taliaferro, Juliana M., Pitner, Mary Kathryn, Browning, Luke S., Lee, Ju-Hyeon, Shen, Yu, Wang, Jian, Ueno, Naoto T., Krishnamurthy, Savitri, Hortobagyi, Gabriel N., Tripathy, Debu, Van Laere, Steven J., Bartholomeusz, Geoffrey, Dalby, Kevin N., Bartholomeusz, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281291/
https://www.ncbi.nlm.nih.gov/pubmed/37377604
http://dx.doi.org/10.1158/2767-9764.CRC-22-0330

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