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Genetic modulation of the HTR2A gene reduces anxiety-related behavior in mice

The expanding field of precision gene editing using CRISPR/Cas9 has demonstrated its potential as a transformative technology in the treatment of various diseases. However, whether this genome-editing tool could be used to modify neural circuits in the central nervous system (CNS), which are implica...

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Detalles Bibliográficos
Autores principales:	Rohn, Troy T, Radin, Dean, Brandmeyer, Tracy, Linder, Barry J, Andriambeloson, Emile, Wagner, Stéphanie, Kehler, James, Vasileva, Ana, Wang, Huaien, Mee, John L, Fallon, James H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Biological, Health, and Medical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281383/ https://www.ncbi.nlm.nih.gov/pubmed/37346271 http://dx.doi.org/10.1093/pnasnexus/pgad170

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