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Reconstructed human intestinal comet assay, a possible alternative in vitro model for genotoxicity assessment

The aim of the present study was to evaluate the compatibility of reconstructed 3D human small intestinal microtissues to perform the in vitro comet assay. The comet assay is a common follow-up genotoxicity test to confirm or supplement other genotoxicity data. Technically, it can be performed utili...

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Detalles Bibliográficos
Autores principales: Hughes, Christopher Owen, Lim, Hui Kheng, Tan, Joseph Choon Wee, Leavesley, David Ian, Smith, Benjamin Paul Chapman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281391/
https://www.ncbi.nlm.nih.gov/pubmed/37115513
http://dx.doi.org/10.1093/mutage/gead011

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