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RTK signalling promotes epithelial columnar cell shape and apical junction maintenance in human lung progenitor cells

Multipotent epithelial progenitor cells can be expanded from human embryonic lungs as organoids and maintained in a self-renewing state using a defined medium. The organoid cells are columnar, resembling the cell morphology of the developing lung tip epithelium in vivo. Cell shape dynamics and fate...

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Detalles Bibliográficos
Autores principales:	Liu, Shuyu, Sun, Dawei, Butler, Richard, Rawlins, Emma L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Human Development
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281517/ https://www.ncbi.nlm.nih.gov/pubmed/37260147 http://dx.doi.org/10.1242/dev.201284

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