Cargando…
Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells
Polydom is an extracellular matrix protein involved in lymphatic vessel development. Polydom-deficient mice die immediately after birth due to defects in lymphatic vessel remodeling, but the mechanism involved is poorly understood. Here, we report that Polydom directly binds to Tie1, an orphan recep...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281526/ https://www.ncbi.nlm.nih.gov/pubmed/37338522 http://dx.doi.org/10.1083/jcb.202208047 |