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Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells

Polydom is an extracellular matrix protein involved in lymphatic vessel development. Polydom-deficient mice die immediately after birth due to defects in lymphatic vessel remodeling, but the mechanism involved is poorly understood. Here, we report that Polydom directly binds to Tie1, an orphan recep...

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Detalles Bibliográficos
Autores principales:	Sato-Nishiuchi, Ryoko, Doiguchi, Masamichi, Morooka, Nanami, Sekiguchi, Kiyotoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281526/ https://www.ncbi.nlm.nih.gov/pubmed/37338522 http://dx.doi.org/10.1083/jcb.202208047

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