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Apoptosis-targeted gene therapy for non-small cell lung cancer using chitosan-poly-lactic-co-glycolic acid -based nano-delivery system and CASP8 and miRs 29A-B1 and 34A

Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide, with resistance to apoptosis being a major driver of therapeutic resistance and aggressive phenotype. This study aimed to develop a novel gene therapy approach for NSCLC by targeting resistance to apoptosis. Lo...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Sourav, Sarkar, Shashanka Shekhar, Saproo, Sheetanshu, Yadav, Sheetal, Antil, Deepika, Das, Bodhisatwa, Naidu, Srivatsava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281530/
https://www.ncbi.nlm.nih.gov/pubmed/37346791
http://dx.doi.org/10.3389/fbioe.2023.1188652

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