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The impact of cell size on morphogen gradient precision

Tissue patterning during embryonic development is remarkably precise. Here, we numerically determine the impact of the cell diameter, gradient length and the morphogen source on the variability of morphogen gradients. We show that the positional error increases with the gradient length relative to t...

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Detalles Bibliográficos
Autores principales: Adelmann, Jan A., Vetter, Roman, Iber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281552/
https://www.ncbi.nlm.nih.gov/pubmed/37249125
http://dx.doi.org/10.1242/dev.201702