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Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians

PURPOSE: The aim of the study is to analyze the swept source-optical coherence tomography angiography (SS-OCTA) characteristics of polypoidal lesions in Caucasian patients. METHODS: In this retrospective observational case series, 43 polypoidal lesions in 32 eyes of 32 patients were diagnosed using...

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Autores principales: Ahmed-Balestra, Daniel, Graf, Alexandra, Stattin, Martin, Haas, Anna-Maria, Kickinger, Stefan, Jacob, Michael, Zehetner, Claus, Krepler, Katharina, Ansari-Shahrezaei, Siamak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281822/
https://www.ncbi.nlm.nih.gov/pubmed/37347074
http://dx.doi.org/10.1155/2023/9597673
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author Ahmed-Balestra, Daniel
Graf, Alexandra
Stattin, Martin
Haas, Anna-Maria
Kickinger, Stefan
Jacob, Michael
Zehetner, Claus
Krepler, Katharina
Ansari-Shahrezaei, Siamak
author_facet Ahmed-Balestra, Daniel
Graf, Alexandra
Stattin, Martin
Haas, Anna-Maria
Kickinger, Stefan
Jacob, Michael
Zehetner, Claus
Krepler, Katharina
Ansari-Shahrezaei, Siamak
author_sort Ahmed-Balestra, Daniel
collection PubMed
description PURPOSE: The aim of the study is to analyze the swept source-optical coherence tomography angiography (SS-OCTA) characteristics of polypoidal lesions in Caucasian patients. METHODS: In this retrospective observational case series, 43 polypoidal lesions in 32 eyes of 32 patients were diagnosed using indocyanine green angiography (ICGA) and compared to SS-OCTA at a tertiary medical retina center (Clinic Landstraße, Vienna Healthcare Group, Austria) between June 2017 and March 2020. Vascularity was identified by color-coded B-scan SS-OCTA while morphology was described as revealed by en face SS-OCTA after alignment with ICGA-confirmed findings. RESULTS: In total, SS-OCTA detected all polypoidal lesions, as identified by ICGA. On B-scan SS-OCTA, circumscribed flow was detected in 33 (76.7%) polypoidal lesions and diffuse flow in 10 (23.3%) lesions. On en face SS-OCTA, polypoidal lesions appeared morphologically as 19 tangled vessel balls (44.2%), 6 tangled vessel balls next to dilated vessels (13.9%), 8 vascular dilatations (18.6%), and 8 ill-defined vascular networks (18.6%), leaving 2 lesions (4.6%) undetected. Circumscribed flow was significantly associated with tangled vessel balls (p = 0.005). CONCLUSION: This study highlights the importance of a multimodal imaging approach, including SS-OCTA, for the evaluation of polypoidal lesions. Our findings suggest a morphological heterogeneity of vascular patterns in Caucasian patients with polypoidal lesions, as pictured by SS-OCTA.
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spelling pubmed-102818222023-06-21 Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians Ahmed-Balestra, Daniel Graf, Alexandra Stattin, Martin Haas, Anna-Maria Kickinger, Stefan Jacob, Michael Zehetner, Claus Krepler, Katharina Ansari-Shahrezaei, Siamak J Ophthalmol Research Article PURPOSE: The aim of the study is to analyze the swept source-optical coherence tomography angiography (SS-OCTA) characteristics of polypoidal lesions in Caucasian patients. METHODS: In this retrospective observational case series, 43 polypoidal lesions in 32 eyes of 32 patients were diagnosed using indocyanine green angiography (ICGA) and compared to SS-OCTA at a tertiary medical retina center (Clinic Landstraße, Vienna Healthcare Group, Austria) between June 2017 and March 2020. Vascularity was identified by color-coded B-scan SS-OCTA while morphology was described as revealed by en face SS-OCTA after alignment with ICGA-confirmed findings. RESULTS: In total, SS-OCTA detected all polypoidal lesions, as identified by ICGA. On B-scan SS-OCTA, circumscribed flow was detected in 33 (76.7%) polypoidal lesions and diffuse flow in 10 (23.3%) lesions. On en face SS-OCTA, polypoidal lesions appeared morphologically as 19 tangled vessel balls (44.2%), 6 tangled vessel balls next to dilated vessels (13.9%), 8 vascular dilatations (18.6%), and 8 ill-defined vascular networks (18.6%), leaving 2 lesions (4.6%) undetected. Circumscribed flow was significantly associated with tangled vessel balls (p = 0.005). CONCLUSION: This study highlights the importance of a multimodal imaging approach, including SS-OCTA, for the evaluation of polypoidal lesions. Our findings suggest a morphological heterogeneity of vascular patterns in Caucasian patients with polypoidal lesions, as pictured by SS-OCTA. Hindawi 2023-06-13 /pmc/articles/PMC10281822/ /pubmed/37347074 http://dx.doi.org/10.1155/2023/9597673 Text en Copyright © 2023 Daniel Ahmed-Balestra et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ahmed-Balestra, Daniel
Graf, Alexandra
Stattin, Martin
Haas, Anna-Maria
Kickinger, Stefan
Jacob, Michael
Zehetner, Claus
Krepler, Katharina
Ansari-Shahrezaei, Siamak
Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians
title Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians
title_full Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians
title_fullStr Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians
title_full_unstemmed Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians
title_short Optical Coherence Tomography Angiography Characteristics of Polypoidal Lesions in Caucasians
title_sort optical coherence tomography angiography characteristics of polypoidal lesions in caucasians
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281822/
https://www.ncbi.nlm.nih.gov/pubmed/37347074
http://dx.doi.org/10.1155/2023/9597673
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