Cargando…

The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis: Nrf2/HMGB1 affects osteoarthritis

Osteoarthritis (OA) is a degenerative or posttraumatic condition of the joints. In OA chondrocytes, Nrf2 functions as a stress response regulator with antioxidant and anti-inflammatory effects. This study aims to investigate the role of Nrf2 and its downstream pathway in the development of osteoarth...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wenzhao, Tao, Cheng, Mao, Minzhi, Zhu, Kewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281874/
https://www.ncbi.nlm.nih.gov/pubmed/37232576
http://dx.doi.org/10.3724/abbs.2023078