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Biochemical mechanism of erastin-induced ferroptotic cell death in neuronal cells: Role of PDI in ferroptosis

Ferroptosis is a new form of nonapoptotic cell death closely associated with glutathione (GSH) peroxidase 4 inhibition and/or GSH depletion, resulting in the accumulation of cellular iron and lipid peroxides. The exact mechanism by which GSH depletion causes the accumulation of reactive oxygen speci...

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Detalles Bibliográficos
Autores principales: Hou, Ming-Jie, Wang, Pan, Zhu, Bao Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281880/
https://www.ncbi.nlm.nih.gov/pubmed/37249331
http://dx.doi.org/10.3724/abbs.2023058

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