Dynamic interplay between target search and recognition for a Type I CRISPR-Cas system

CRISPR-Cas effector complexes enable the defense against foreign nucleic acids and have recently been exploited as molecular tools for precise genome editing at a target locus. To bind and cleave their target, the CRISPR-Cas effectors have to interrogate the entire genome for the presence of a match...

Descripción completa

Detalles Bibliográficos
Autores principales: Aldag, Pierre, Rutkauskas, Marius, Madariaga-Marcos, Julene, Songailiene, Inga, Sinkunas, Tomas, Kemmerich, Felix, Kauert, Dominik, Siksnys, Virginijus, Seidel, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281945/
https://www.ncbi.nlm.nih.gov/pubmed/37339984
http://dx.doi.org/10.1038/s41467-023-38790-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281945/
https://www.ncbi.nlm.nih.gov/pubmed/37339984
http://dx.doi.org/10.1038/s41467-023-38790-1

Ejemplares similares