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Dynamic interplay between target search and recognition for a Type I CRISPR-Cas system

CRISPR-Cas effector complexes enable the defense against foreign nucleic acids and have recently been exploited as molecular tools for precise genome editing at a target locus. To bind and cleave their target, the CRISPR-Cas effectors have to interrogate the entire genome for the presence of a match...

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Detalles Bibliográficos
Autores principales:	Aldag, Pierre, Rutkauskas, Marius, Madariaga-Marcos, Julene, Songailiene, Inga, Sinkunas, Tomas, Kemmerich, Felix, Kauert, Dominik, Siksnys, Virginijus, Seidel, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281945/ https://www.ncbi.nlm.nih.gov/pubmed/37339984 http://dx.doi.org/10.1038/s41467-023-38790-1

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