Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas

The extracellular microenvironment modulates glioma behaviour. It remains unknown if blood-brain barrier disruption merely reflects or functionally supports glioma aggressiveness. We utilised intra-operative microdialysis to sample the extracellular metabolome of radiographically diverse regions of...

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Detalles Bibliográficos
Autores principales: Riviere-Cazaux, Cecile, Carlstrom, Lucas P., Rajani, Karishma, Munoz-Casabella, Amanda, Rahman, Masum, Gharibi-Loron, Ali, Brown, Desmond A., Miller, Kai J., White, Jaclyn J., Himes, Benjamin T., Jusue-Torres, Ignacio, Ikram, Samar, Ransom, Seth C., Hirte, Renee, Oh, Ju-Hee, Elmquist, William F., Sarkaria, Jann N., Vaubel, Rachael A., Rodriguez, Moses, Warrington, Arthur E., Kizilbash, Sani H., Burns, Terry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281947/
https://www.ncbi.nlm.nih.gov/pubmed/37340056
http://dx.doi.org/10.1038/s42003-023-05035-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281947/
https://www.ncbi.nlm.nih.gov/pubmed/37340056
http://dx.doi.org/10.1038/s42003-023-05035-2

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