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A screening method for cervical myelopathy using machine learning to analyze a drawing behavior

Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, t...

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Autores principales: Yamada, Eriku, Fujita, Koji, Watanabe, Takuro, Koyama, Takafumi, Ibara, Takuya, Yamamoto, Akiko, Tsukamoto, Kazuya, Kaburagi, Hidetoshi, Nimura, Akimoto, Yoshii, Toshitaka, Sugiura, Yuta, Okawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281965/
https://www.ncbi.nlm.nih.gov/pubmed/37340079
http://dx.doi.org/10.1038/s41598-023-37253-3
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author Yamada, Eriku
Fujita, Koji
Watanabe, Takuro
Koyama, Takafumi
Ibara, Takuya
Yamamoto, Akiko
Tsukamoto, Kazuya
Kaburagi, Hidetoshi
Nimura, Akimoto
Yoshii, Toshitaka
Sugiura, Yuta
Okawa, Atsushi
author_facet Yamada, Eriku
Fujita, Koji
Watanabe, Takuro
Koyama, Takafumi
Ibara, Takuya
Yamamoto, Akiko
Tsukamoto, Kazuya
Kaburagi, Hidetoshi
Nimura, Akimoto
Yoshii, Toshitaka
Sugiura, Yuta
Okawa, Atsushi
author_sort Yamada, Eriku
collection PubMed
description Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, the participants traced three different shapes displayed on a tablet device. During the tasks, writing behaviors, such as the coordinates, velocity, and pressure of the stylus tip, along with the drawing time, were recorded. From these data, features related to the drawing pressure, and time to trace each shape and combination of shapes were used as training data for the support vector machine, a machine learning algorithm. To evaluate the accuracy, a receiver operating characteristic curve was generated, and the area under the curve (AUC) was calculated. Models with triangular waveforms tended to be the most accurate. The best triangular wave model identified patients with and without CM with 76% sensitivity and 76% specificity, yielding an AUC of 0.80. Our model was able to classify CM with high accuracy and could be applied to the development of disease screening systems useful outside the hospital setting.
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spelling pubmed-102819652023-06-22 A screening method for cervical myelopathy using machine learning to analyze a drawing behavior Yamada, Eriku Fujita, Koji Watanabe, Takuro Koyama, Takafumi Ibara, Takuya Yamamoto, Akiko Tsukamoto, Kazuya Kaburagi, Hidetoshi Nimura, Akimoto Yoshii, Toshitaka Sugiura, Yuta Okawa, Atsushi Sci Rep Article Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, the participants traced three different shapes displayed on a tablet device. During the tasks, writing behaviors, such as the coordinates, velocity, and pressure of the stylus tip, along with the drawing time, were recorded. From these data, features related to the drawing pressure, and time to trace each shape and combination of shapes were used as training data for the support vector machine, a machine learning algorithm. To evaluate the accuracy, a receiver operating characteristic curve was generated, and the area under the curve (AUC) was calculated. Models with triangular waveforms tended to be the most accurate. The best triangular wave model identified patients with and without CM with 76% sensitivity and 76% specificity, yielding an AUC of 0.80. Our model was able to classify CM with high accuracy and could be applied to the development of disease screening systems useful outside the hospital setting. Nature Publishing Group UK 2023-06-20 /pmc/articles/PMC10281965/ /pubmed/37340079 http://dx.doi.org/10.1038/s41598-023-37253-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Yamada, Eriku
Fujita, Koji
Watanabe, Takuro
Koyama, Takafumi
Ibara, Takuya
Yamamoto, Akiko
Tsukamoto, Kazuya
Kaburagi, Hidetoshi
Nimura, Akimoto
Yoshii, Toshitaka
Sugiura, Yuta
Okawa, Atsushi
A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
title A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
title_full A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
title_fullStr A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
title_full_unstemmed A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
title_short A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
title_sort screening method for cervical myelopathy using machine learning to analyze a drawing behavior
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281965/
https://www.ncbi.nlm.nih.gov/pubmed/37340079
http://dx.doi.org/10.1038/s41598-023-37253-3
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