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A screening method for cervical myelopathy using machine learning to analyze a drawing behavior
Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281965/ https://www.ncbi.nlm.nih.gov/pubmed/37340079 http://dx.doi.org/10.1038/s41598-023-37253-3 |
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author | Yamada, Eriku Fujita, Koji Watanabe, Takuro Koyama, Takafumi Ibara, Takuya Yamamoto, Akiko Tsukamoto, Kazuya Kaburagi, Hidetoshi Nimura, Akimoto Yoshii, Toshitaka Sugiura, Yuta Okawa, Atsushi |
author_facet | Yamada, Eriku Fujita, Koji Watanabe, Takuro Koyama, Takafumi Ibara, Takuya Yamamoto, Akiko Tsukamoto, Kazuya Kaburagi, Hidetoshi Nimura, Akimoto Yoshii, Toshitaka Sugiura, Yuta Okawa, Atsushi |
author_sort | Yamada, Eriku |
collection | PubMed |
description | Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, the participants traced three different shapes displayed on a tablet device. During the tasks, writing behaviors, such as the coordinates, velocity, and pressure of the stylus tip, along with the drawing time, were recorded. From these data, features related to the drawing pressure, and time to trace each shape and combination of shapes were used as training data for the support vector machine, a machine learning algorithm. To evaluate the accuracy, a receiver operating characteristic curve was generated, and the area under the curve (AUC) was calculated. Models with triangular waveforms tended to be the most accurate. The best triangular wave model identified patients with and without CM with 76% sensitivity and 76% specificity, yielding an AUC of 0.80. Our model was able to classify CM with high accuracy and could be applied to the development of disease screening systems useful outside the hospital setting. |
format | Online Article Text |
id | pubmed-10281965 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-102819652023-06-22 A screening method for cervical myelopathy using machine learning to analyze a drawing behavior Yamada, Eriku Fujita, Koji Watanabe, Takuro Koyama, Takafumi Ibara, Takuya Yamamoto, Akiko Tsukamoto, Kazuya Kaburagi, Hidetoshi Nimura, Akimoto Yoshii, Toshitaka Sugiura, Yuta Okawa, Atsushi Sci Rep Article Early detection of cervical myelopathy (CM) is important for a favorable outcome, as its prognosis is poor when left untreated. We developed a screening method for CM using machine learning-based analysis of the drawing behavior of 38 patients with CM and 66 healthy volunteers. Using a stylus pen, the participants traced three different shapes displayed on a tablet device. During the tasks, writing behaviors, such as the coordinates, velocity, and pressure of the stylus tip, along with the drawing time, were recorded. From these data, features related to the drawing pressure, and time to trace each shape and combination of shapes were used as training data for the support vector machine, a machine learning algorithm. To evaluate the accuracy, a receiver operating characteristic curve was generated, and the area under the curve (AUC) was calculated. Models with triangular waveforms tended to be the most accurate. The best triangular wave model identified patients with and without CM with 76% sensitivity and 76% specificity, yielding an AUC of 0.80. Our model was able to classify CM with high accuracy and could be applied to the development of disease screening systems useful outside the hospital setting. Nature Publishing Group UK 2023-06-20 /pmc/articles/PMC10281965/ /pubmed/37340079 http://dx.doi.org/10.1038/s41598-023-37253-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Yamada, Eriku Fujita, Koji Watanabe, Takuro Koyama, Takafumi Ibara, Takuya Yamamoto, Akiko Tsukamoto, Kazuya Kaburagi, Hidetoshi Nimura, Akimoto Yoshii, Toshitaka Sugiura, Yuta Okawa, Atsushi A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
title | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
title_full | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
title_fullStr | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
title_full_unstemmed | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
title_short | A screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
title_sort | screening method for cervical myelopathy using machine learning to analyze a drawing behavior |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281965/ https://www.ncbi.nlm.nih.gov/pubmed/37340079 http://dx.doi.org/10.1038/s41598-023-37253-3 |
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