SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells

The cystine transporter solute carrier family 7 member 11 (SLC7A11; also called xCT) protects cancer cells from oxidative stress and is overexpressed in many cancers. Here we report a surprising finding that, whereas moderate overexpression of SLC7A11 is beneficial for cancer cells treated with H(2)...

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Detalles Bibliográficos
Autores principales: Yan, Yuelong, Teng, Hongqi, Hang, Qinglei, Kondiparthi, Lavanya, Lei, Guang, Horbath, Amber, Liu, Xiaoguang, Mao, Chao, Wu, Shiqi, Zhuang, Li, James You, M., Poyurovsky, Masha V., Ma, Li, Olszewski, Kellen, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281978/
https://www.ncbi.nlm.nih.gov/pubmed/37339981
http://dx.doi.org/10.1038/s41467-023-39401-9

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