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An oral cancer vaccine using Bifidobacterium vector augments combination of anti-PD-1 and anti-CTLA-4 antibodies in mouse renal cell carcinoma model
Recently, immune checkpoint inhibitor (ICI) based combination therapies, including anti-PD-1 antibody, nivolumab with anti-CTLA-4 antibody, and ipilimumab have become the primary treatment option for metastatic or unresectable renal cell carcinoma (RCC). However, despite the combination of two ICIs,...
Autores principales: | Ueki, Hideto, Kitagawa, Koichi, Kato, Mako, Yanase, Shihoko, Okamura, Yasuyoshi, Bando, Yukari, Hara, Takuto, Terakawa, Tomoaki, Furukawa, Junya, Nakano, Yuzo, Fujisawa, Masato, Shirakawa, Toshiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281997/ https://www.ncbi.nlm.nih.gov/pubmed/37340017 http://dx.doi.org/10.1038/s41598-023-37234-6 |
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