Cargando…

Causal factors in primary open angle glaucoma: a phenome-wide Mendelian randomisation study

Primary open angle glaucoma (POAG) is a chronic, adult-onset optic neuropathy associated with characteristic optic disc and/or visual field changes. With a view to identifying modifiable risk factors for this common neurodegenerative condition, we performed a ‘phenome-wide’ univariable Mendelian ran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Julian, Thomas H., Girach, Zain, Sanderson, Eleanor, Guo, Hui, Yu, Jonathan, Cooper-Knock, Johnathan, Black, Graeme C., Sergouniotis, Panagiotis I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282034/ https://www.ncbi.nlm.nih.gov/pubmed/37340071 http://dx.doi.org/10.1038/s41598-023-37144-7

Ejemplares similares

Phenome-wide Mendelian randomisation analysis identifies causal factors for age-related macular degeneration
por: Julian, Thomas H, et al.
Publicado: (2023)

Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study
por: Saunders, Charlie N., et al.
Publicado: (2020)

A phenome-wide bidirectional Mendelian randomization analysis of atrial fibrillation
por: Wang, Qin, et al.
Publicado: (2022)

Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
por: Yuan, Shuai, et al.
Publicado: (2022)

Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study
por: Magnus, Maria C., et al.
Publicado: (2020)

Identifying potential causal effects of age at menopause: a Mendelian randomization phenome-wide association study
por: Magnus, Maria C., et al.
Publicado: (2022)

The Causal Relationships Between Extrinsic Exposures and Risk of Prostate Cancer: A Phenome-Wide Mendelian Randomization Study
por: Gu, Dongqing, et al.
Publicado: (2022)

The Causal Association of Irritable Bowel Syndrome with Multiple Disease Outcomes: A Phenome-Wide Mendelian Randomization Study
por: Li, Chunyang, et al.
Publicado: (2023)

Identifying the potential causal role of insomnia symptoms on 11,409 health-related outcomes: a phenome-wide Mendelian randomisation analysis in UK Biobank
por: Gibson, Mark J., et al.
Publicado: (2023)

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
por: Shen, Xueyi, et al.
Publicado: (2020)

The Causal Effects of Blood Iron and Copper on Lipid Metabolism Diseases: Evidence from Phenome-Wide Mendelian Randomization Study
por: Zhou, Jingqi, et al.
Publicado: (2020)

Causal Association between Iritis or Uveitis and Glaucoma: A Two-Sample Mendelian Randomisation Study
por: Seo, Je Hyun, et al.
Publicado: (2023)

The Causal Association Between Obesity and Primary Open-Angle Glaucoma: A Two-Sample Mendelian Randomization Study
por: Lin, Yi, et al.
Publicado: (2022)

Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study
por: Yu, Xinzhu, et al.
Publicado: (2023)

Investigating causality in the association between DNA methylation and type 2 diabetes using bidirectional two-sample Mendelian randomisation
por: Juvinao-Quintero, Diana L., et al.
Publicado: (2023)

Health effects of milk consumption: phenome-wide Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2022)

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study
por: Dong, Shan-Shan, et al.
Publicado: (2021)

Mendelian Randomisation and Causal Inference in Observational Epidemiology
por: Sheehan, Nuala A, et al.
Publicado: (2008)

Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study
por: Zagkos, Loukas, et al.
Publicado: (2022)

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
por: Zheng, Jie, et al.
Publicado: (2020)

The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization
por: Korologou-Linden, Roxanna, et al.
Publicado: (2022)

Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes
por: Julian, Thomas H, et al.
Publicado: (2021)

Education and myopia: assessing the direction of causality by mendelian randomisation
Publicado: (2018)

Education and myopia: assessing the direction of causality by mendelian randomisation
por: Mountjoy, Edward, et al.
Publicado: (2018)

Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits
por: Park, Joshua K, et al.
Publicado: (2023)

Implicating Causal Brain Magnetic Resonance Imaging in Glaucoma Using Mendelian Randomization
por: Liu, Kangcheng, et al.
Publicado: (2022)

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks
por: Amar, David, et al.
Publicado: (2021)

USING MENDELIAN RANDOMISATION TO INFER CAUSALITY IN DEPRESSION AND ANXIETY RESEARCH
por: Gage, Suzanne H, et al.
Publicado: (2014)

Cigarette smoking and personality: interrogating causality using Mendelian randomisation
por: Sallis, Hannah M., et al.
Publicado: (2019)

Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour
por: Sanderson, Eleanor, et al.
Publicado: (2019)

Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework
por: Cho, Yoonsu, et al.
Publicado: (2020)

Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization
por: Sanderson, Eleanor, et al.
Publicado: (2022)

Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigation
por: Yuan, Shuai, et al.
Publicado: (2022)

Phenome-wide Mendelian randomization study evaluating the association of circulating vitamin D with complex diseases
por: Xu, Jin-jian, et al.
Publicado: (2023)

Educational inequality in multimorbidity: causality and causal pathways. A mendelian randomisation study in UK Biobank
por: North, Teri-Louise, et al.
Publicado: (2023)

Causal association between common rheumatic diseases and glaucoma: a Mendelian randomization study
por: Meng, Yang, et al.
Publicado: (2023)

A phenome-wide approach to identify causal risk factors for deep vein thrombosis
por: Constantinescu, Andrei-Emil, et al.
Publicado: (2023)

Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls
por: Went, Molly, et al.
Publicado: (2023)

Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls
por: Went, Molly, et al.
Publicado: (2023)

Cannabis use and the risk of primary open-angle glaucoma: a Mendelian randomization study
por: Katsimpris, Andreas, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lv2lh39md53cjp3bh19hk8kpdf