Intraperitoneal paclitaxel combined with FOLFOX/CAPOX plus bevacizumab for colorectal cancer with peritoneal carcinomatosis (the iPac-02 trial): study protocol of a single arm, multicenter, phase 2 study

BACKGROUND: The safety of intraperitoneally administrated paclitaxel (op PTX) was demonstrated in the phase I trial of ip PTX combined with conventional systemic chemotherapy for colorectal cancer with peritoneal carcinomatosis. Moreover, the median survival time was 29.3 months, which was longer th...

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Detalles Bibliográficos
Autores principales: Murono, Koji, Yokoyama, Yuichiro, Nozawa, Hiroaki, Sasaki, Kazuhito, Emoto, Shigenobu, Matsuzaki, Hiroyuki, Kashiwabara, Kosuke, Ishigami, Hironori, Gohda, Yoshimasa, Yamaguchi, Hironori, Kitayama, Joji, Ishihara, Soichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282041/
https://www.ncbi.nlm.nih.gov/pubmed/37340243
http://dx.doi.org/10.1007/s00384-023-04434-5

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