ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review

KEY CLINICAL MESSAGE: Patients with antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis, specifically with myeloperoxidase (MPO)‐ANCA, would have a risk for developing corneal melt and perforation abruptly in a short period. It is desirable to have a team of collaboration of rheumatolog...

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Autores principales: Matsuo, Toshihiko, Hiramatsu‐Asano, Sumie, Sawachika, Hiroshi, Nishimura, Hirotake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282114/
https://www.ncbi.nlm.nih.gov/pubmed/37351359
http://dx.doi.org/10.1002/ccr3.7595
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author Matsuo, Toshihiko
Hiramatsu‐Asano, Sumie
Sawachika, Hiroshi
Nishimura, Hirotake
author_facet Matsuo, Toshihiko
Hiramatsu‐Asano, Sumie
Sawachika, Hiroshi
Nishimura, Hirotake
author_sort Matsuo, Toshihiko
collection PubMed
description KEY CLINICAL MESSAGE: Patients with antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis, specifically with myeloperoxidase (MPO)‐ANCA, would have a risk for developing corneal melt and perforation abruptly in a short period. It is desirable to have a team of collaboration of rheumatologists and other specialties. ABSTRACT: An 80‐year old man who had been diagnosed 5.5 years previously as ANCA‐associated vasculitis by temporal artery biopsy developed corneal melt and perforation with scleritis in both eyes. He underwent successful cataract surgery and retained ambulatory vision with the aid of intravenous rituximab. Two additional patients with similar manifestations were found in the literature.
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spelling pubmed-102821142023-06-22 ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review Matsuo, Toshihiko Hiramatsu‐Asano, Sumie Sawachika, Hiroshi Nishimura, Hirotake Clin Case Rep Case Report KEY CLINICAL MESSAGE: Patients with antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis, specifically with myeloperoxidase (MPO)‐ANCA, would have a risk for developing corneal melt and perforation abruptly in a short period. It is desirable to have a team of collaboration of rheumatologists and other specialties. ABSTRACT: An 80‐year old man who had been diagnosed 5.5 years previously as ANCA‐associated vasculitis by temporal artery biopsy developed corneal melt and perforation with scleritis in both eyes. He underwent successful cataract surgery and retained ambulatory vision with the aid of intravenous rituximab. Two additional patients with similar manifestations were found in the literature. John Wiley and Sons Inc. 2023-06-20 /pmc/articles/PMC10282114/ /pubmed/37351359 http://dx.doi.org/10.1002/ccr3.7595 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Matsuo, Toshihiko
Hiramatsu‐Asano, Sumie
Sawachika, Hiroshi
Nishimura, Hirotake
ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review
title ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review
title_full ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review
title_fullStr ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review
title_full_unstemmed ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review
title_short ANCA‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: Case report and literature review
title_sort anca‐associated vasculitis with scleritis, corneal melt, and perforation rescued by rituximab: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282114/
https://www.ncbi.nlm.nih.gov/pubmed/37351359
http://dx.doi.org/10.1002/ccr3.7595
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