Metabolic reprogramming through mitochondrial biogenesis drives adenosine anti-inflammatory effects: new mechanism controlling gingival fibroblast hyper-inflammatory state

INTRODUCTION: Fibroblasts are the dominant stromal cells in the gingival lamina propria with a well-established relevance in regulation of inflammation, and in innate immunity. This is exemplified by their hypersecretion of CXCL8, enhancing leukocyte infiltration in chronic and sustained inflammator...

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Detalles Bibliográficos
Autores principales: Paladines, Nathalie, Dawson, Shantiece, Ryan, Weston, Serrano-Lopez, Rogelio, Messer, Regina, Huo, Yuqing, Cutler, Christopher W., Ramos-Junior, Erivan S., Morandini, Ana Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282177/
https://www.ncbi.nlm.nih.gov/pubmed/37350964
http://dx.doi.org/10.3389/fimmu.2023.1148216

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