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A transistor model for the cystic fibrosis transmembrane conductance regulator

In this paper we present a transistor circuit model for cystic fibrosis transmembrane conductance regulator (CFTR) that seeks to map the functional form of CFTR both in wild type and mutants. The circuit architecture is configured so that the function, and as much as possible the form, faithfully re...

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Detalles Bibliográficos
Autores principales: Hunt, William D., McCarty, Nael A., Marin, Eduardo Martinez, Westafer, Ryan S., Yamin, Phillip R., Cui, Guiying, Eckford, Andrew W., Denison, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282560/
https://www.ncbi.nlm.nih.gov/pubmed/37351179
http://dx.doi.org/10.1016/j.bpr.2023.100108