Cargando…

A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and myopia

Introduction: Long axial length (AL) is a risk factor for myopia. Although family studies indicate that AL has an important genetic component with heritability estimates up to 0.94, there have been few reports of AL-associated loci. Methods: Here, we conducted a multiethnic genome-wide association s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Chen, Melles, Ronald B., Yin, Jie, Fan, Qiao, Guo, Xiaobo, Cheng, Ching-Yu, He, Mingguang, Mackey, David A., Guggenheim, Jeremy A., Klaver, Caroline, Nair, K. Saidas, Jorgenson, Eric, Choquet, Hélène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282939/ https://www.ncbi.nlm.nih.gov/pubmed/37351342 http://dx.doi.org/10.3389/fgene.2023.1113058

Ejemplares similares

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects
por: Choquet, Hélène, et al.
Publicado: (2021)

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci
por: Choquet, Hélène, et al.
Publicado: (2018)

A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness
por: Choquet, Hélène, et al.
Publicado: (2020)

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia
por: Hysi, Pirro G., et al.
Publicado: (2020)

A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration
por: Clark, Rosie, et al.
Publicado: (2023)

A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure
por: Choquet, Hélène, et al.
Publicado: (2017)

Non-additive (dominance) effects of genetic variants associated with refractive error and myopia
por: Pozarickij, Alfred, et al.
Publicado: (2020)

Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci
por: Shah, Rupal L., et al.
Publicado: (2018)

Categorisation of myopia progression by change in refractive error and axial elongation and their impact on benefit of myopia control using orthokeratology
por: Cho, Pauline, et al.
Publicado: (2020)

Axial length growth and the risk of developing myopia in European children
por: Tideman, Jan Willem Lodewijk, et al.
Publicado: (2017)

New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis
por: Choquet, Hélène, et al.
Publicado: (2021)

APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans
por: Tkatchenko, Andrei V., et al.
Publicado: (2015)

Rare variant analyses across multiethnic cohorts identify novel genes for refractive error
por: Musolf, Anthony M., et al.
Publicado: (2023)

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error
por: Fan, Qiao, et al.
Publicado: (2020)

Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error
por: Paylakhi, Seyyedhassan, et al.
Publicado: (2018)

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium
por: Fan, Qiao, et al.
Publicado: (2016)

Accuracy of axial length, keratometry, and refractive measurement with Myopia Master in children with ametropia
por: Ye, Yuhao, et al.
Publicado: (2022)

Whole exome sequence analysis in 51 624 participants identifies novel genes and variants associated with refractive error and myopia
por: Guggenheim, Jeremy A, et al.
Publicado: (2022)

Relationship between peripheral refraction, axial lengths and parental myopia of young adult myopes
por: Koomson, Nana Yaa, et al.
Publicado: (2022)

Identifying Children at Risk of High Myopia Using Population Centile Curves of Refraction
por: Chen, Yanxian, et al.
Publicado: (2016)

Axial growth and refractive change in white European children and young adults: predictive factors for myopia
por: McCullough, Sara, et al.
Publicado: (2020)

Longitudinal Changes in Axial Length and Spherical Equivalent in Children and Adolescents With High Myopia
por: Jiang, Feng, et al.
Publicado: (2023)

IMI – Myopia Genetics Report
por: Tedja, Milly S., et al.
Publicado: (2019)

Distribution of Axial Length in Australians of Different Age Groups, Ethnicities, and Refractive Errors
por: Nilagiri, Vinay Kumar, et al.
Publicado: (2023)

Effects of atropine 0.01% on refractive errors in children with myopia
por: Zhu, Xingxue, et al.
Publicado: (2023)

Assessing the contribution of genetic nurture to refractive error
por: Guggenheim, Jeremy A., et al.
Publicado: (2022)

Oral crocetin administration suppressed refractive shift and axial elongation in a murine model of lens-induced myopia
por: Mori, Kiwako, et al.
Publicado: (2019)

Refractive Errors and Risk Factors for Myopia in Primary School Students in Urumqi
por: Liu, Meng, et al.
Publicado: (2022)

Axial Length to Corneal Radius of Curvature Ratio and Refractive Errors
por: Hashemi, Hassan, et al.
Publicado: (2013)

Myopia onset and role of peripheral refraction
por: Rotolo, Maurilia, et al.
Publicado: (2017)

Pathologic myopia and severe pathologic myopia: correlation with axial length
por: Flores-Moreno, Ignacio, et al.
Publicado: (2021)

Prediction of myopia onset with refractive error measured using non-cycloplegic subjective refraction: the WEPrOM Study
por: Wong, Yee Ling, et al.
Publicado: (2021)

Generational difference of refractive error in the baseline study of the Beijing Myopia Progression Study
por: Liang, Yuan Bo, et al.
Publicado: (2013)

Axial length targets for myopia control
por: Chamberlain, Paul, et al.
Publicado: (2021)

The effect of peripheral defocus on axial growth and modulation of refractive error in hyperopes
por: Beasley, Ian G, et al.
Publicado: (2022)

Axial Length/Corneal Radius Ratio: Association with Refractive State and Role on Myopia Detection Combined with Visual Acuity in Chinese Schoolchildren
por: He, Xiangui, et al.
Publicado: (2015)

Baseline peripheral refractive error and changes in axial refraction during one year in a young adult population
por: Hartwig, Andreas, et al.
Publicado: (2016)

Ancestry- and sex-specific effects underlying inguinal hernia susceptibility identified in a multiethnic genome-wide association study meta-analysis
por: Choquet, Hélène, et al.
Publicado: (2022)

Prevalence and risk factors for myopia and other refractive errors in an adult population in southern India
por: Joseph, Sanil, et al.
Publicado: (2018)

Retinal Vascular Oxygen Saturation and Its Variation With Refractive Error and Axial Length
por: Lim, Laurence Shen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_sgsr4n1hpap8srrgvu95965ap1