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Co-expression of Foxp3 and Helios facilitates the identification of human T regulatory cells in health and disease

Foxp3 is regarded as the major transcription factor for T regulatory (T(reg)) cells and expression of Foxp3 is used to identify and quantitate Treg cells in mouse models. However, several studies have demonstrated that human CD4(+) T conventional (T(conv)) cells activated in vitro by T cell receptor...

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Detalles Bibliográficos
Autores principales: Morina, Lyra, Jones, Madalyn E., Oguz, Cihan, Kaplan, Mariana J., Gangaplara, Arunakumar, Fitzhugh, Courtney D., Kanakry, Christopher G., Shevach, Ethan M., Buszko, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282999/
https://www.ncbi.nlm.nih.gov/pubmed/37350974
http://dx.doi.org/10.3389/fimmu.2023.1114780