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A novel hACE2 knock-in mouse model recapitulates pulmonary and intestinal SARS-CoV-2 infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is responsible for the coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) receptor to enter the host, and the gastrointestinal tract is a potential infection site as this r...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoyang, Sun, Weiyang, Zhang, Yu, Gu, Hongjing, Wang, Ruixuan, Xie, Peng, Zhu, Yunkai, Qiu, Minyue, Ding, Xiaoyan, Wang, Hui, Gao, Yuwei, Li, Jintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283006/
https://www.ncbi.nlm.nih.gov/pubmed/37350787
http://dx.doi.org/10.3389/fmicb.2023.1175188