PARP-1: a critical regulator in radioprotection and radiotherapy-mechanisms, challenges, and therapeutic opportunities

Background: Since its discovery, poly (ADP-ribose) polymerase 1 (PARP-1) has been extensively studied due to its regulatory role in numerous biologically crucial pathways. PARP inhibitors have opened new therapeutic avenues for cancer patients and have gained approval as standalone treatments for ce...

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Detalles Bibliográficos
Autores principales: Li, Wen-Hao, Wang, Fei, Song, Gui-Yuan, Yu, Qing-Hua, Du, Rui-Peng, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283042/
https://www.ncbi.nlm.nih.gov/pubmed/37351512
http://dx.doi.org/10.3389/fphar.2023.1198948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283042/
https://www.ncbi.nlm.nih.gov/pubmed/37351512
http://dx.doi.org/10.3389/fphar.2023.1198948

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