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SPI1-mediated MIR222HG transcription promotes proneural-to-mesenchymal transition of glioma stem cells and immunosuppressive polarization of macrophages

Background: Glioma stem cells (GSCs) are a key factor in glioblastoma (GBM) development and treatment resistance. GSCs can be divided into the mesenchymal (MES) and proneural (PN) subtypes, and these two subtypes of GSCs can undergo interconversion under certain conditions. MES GSCs have higher mali...

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Detalles Bibliográficos
Autores principales: Fan, Yang, Gao, Zijie, Xu, Jianye, Wang, Huizhi, Guo, Qindong, Li, Boyan, Li, Ming, Xu, Hao, Qi, Yanhua, Zhao, Shulin, Qiu, Wei, Pan, Ziwen, Wang, Qingtong, Xue, Hao, Zhao, Rongrong, Guo, Xing, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283056/
https://www.ncbi.nlm.nih.gov/pubmed/37351164
http://dx.doi.org/10.7150/thno.82590

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