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Improved extracellular vesicle-based mRNA delivery for familial hypercholesterolemia treatment

Extracellular vesicle (EV)-based low-density lipoprotein receptor (Ldlr) mRNA delivery showed excellent therapeutic effects in treating familial hypercholesterolemia (FH). Nevertheless, the loading inefficiency of EV-based mRNA delivery presents a significant challenge. Recently, RNA-binding protein...

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Detalles Bibliográficos
Autores principales:	Yang, Zheng, Ji, Panpan, Li, Zhelong, Zhang, Rongxin, Wei, Mengying, Yang, Yang, Yuan, Lijun, Han, Yan, Yang, Guodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283059/ https://www.ncbi.nlm.nih.gov/pubmed/37351166 http://dx.doi.org/10.7150/thno.82873

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