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The completeness of the left atrial appendage amputation during routine cardiac surgery

BACKGROUND: Left atrial appendage (LAA) is the origin of most heart thrombi which can lead to stroke or other cerebrovascular event in patients with non-valvular atrial fibrillation (AF). This study aimed to prove safety and low complication rate of surgical LAA amputation using cut and sew techniqu...

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Autores principales: Radakovic, Dejan, Penov, Kiril, Lazarus, Marc, Madrahimov, Nodir, Hamouda, Khaled, Schimmer, Christoph, Leyh, Rainer G., Bening, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283164/
https://www.ncbi.nlm.nih.gov/pubmed/37340354
http://dx.doi.org/10.1186/s12872-023-03330-8
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author Radakovic, Dejan
Penov, Kiril
Lazarus, Marc
Madrahimov, Nodir
Hamouda, Khaled
Schimmer, Christoph
Leyh, Rainer G.
Bening, Constanze
author_facet Radakovic, Dejan
Penov, Kiril
Lazarus, Marc
Madrahimov, Nodir
Hamouda, Khaled
Schimmer, Christoph
Leyh, Rainer G.
Bening, Constanze
author_sort Radakovic, Dejan
collection PubMed
description BACKGROUND: Left atrial appendage (LAA) is the origin of most heart thrombi which can lead to stroke or other cerebrovascular event in patients with non-valvular atrial fibrillation (AF). This study aimed to prove safety and low complication rate of surgical LAA amputation using cut and sew technique with control of its effectiveness. METHODS: 303 patients who have undergone selective LAA amputation were enrolled in the study in a period from 10/17 to 08/20. The LAA amputation was performed concomitant to routine cardiac surgery on cardiopulmonary bypass with cardiac arrest with or without previous history of AF. The operative and clinical data were evaluated. Extent of LAA amputation was examined intraoperatively by transoesophageal echocardiography (TEE). Six months in follow up, the patients were controlled regarding clinical status and episodes of strokes. RESULTS: Average age of study population was 69.9 ± 19.2 and 81.9% of patients were male. In only three patients was residual stump after LAA amputation larger than 1 cm with average stump size 0.28 ± 0.34 cm. 3 patients (1%) developed postoperative bleeding. Postoperatively 77 (25.4%) patients developed postoperative AF (POAF), of which 29 (9.6%) still had AF at discharge. On 6 months follow up only 5 patients had NYHA class III and 1 NYHA class IV. Seven patients reported with leg oedema and no patient experienced any cerebrovascular event in early postoperative follow up. CONCLUSION: LAA amputation can be performed safely and completely leaving minimal to no LAA residual stump.
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spelling pubmed-102831642023-06-22 The completeness of the left atrial appendage amputation during routine cardiac surgery Radakovic, Dejan Penov, Kiril Lazarus, Marc Madrahimov, Nodir Hamouda, Khaled Schimmer, Christoph Leyh, Rainer G. Bening, Constanze BMC Cardiovasc Disord Research BACKGROUND: Left atrial appendage (LAA) is the origin of most heart thrombi which can lead to stroke or other cerebrovascular event in patients with non-valvular atrial fibrillation (AF). This study aimed to prove safety and low complication rate of surgical LAA amputation using cut and sew technique with control of its effectiveness. METHODS: 303 patients who have undergone selective LAA amputation were enrolled in the study in a period from 10/17 to 08/20. The LAA amputation was performed concomitant to routine cardiac surgery on cardiopulmonary bypass with cardiac arrest with or without previous history of AF. The operative and clinical data were evaluated. Extent of LAA amputation was examined intraoperatively by transoesophageal echocardiography (TEE). Six months in follow up, the patients were controlled regarding clinical status and episodes of strokes. RESULTS: Average age of study population was 69.9 ± 19.2 and 81.9% of patients were male. In only three patients was residual stump after LAA amputation larger than 1 cm with average stump size 0.28 ± 0.34 cm. 3 patients (1%) developed postoperative bleeding. Postoperatively 77 (25.4%) patients developed postoperative AF (POAF), of which 29 (9.6%) still had AF at discharge. On 6 months follow up only 5 patients had NYHA class III and 1 NYHA class IV. Seven patients reported with leg oedema and no patient experienced any cerebrovascular event in early postoperative follow up. CONCLUSION: LAA amputation can be performed safely and completely leaving minimal to no LAA residual stump. BioMed Central 2023-06-20 /pmc/articles/PMC10283164/ /pubmed/37340354 http://dx.doi.org/10.1186/s12872-023-03330-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Radakovic, Dejan
Penov, Kiril
Lazarus, Marc
Madrahimov, Nodir
Hamouda, Khaled
Schimmer, Christoph
Leyh, Rainer G.
Bening, Constanze
The completeness of the left atrial appendage amputation during routine cardiac surgery
title The completeness of the left atrial appendage amputation during routine cardiac surgery
title_full The completeness of the left atrial appendage amputation during routine cardiac surgery
title_fullStr The completeness of the left atrial appendage amputation during routine cardiac surgery
title_full_unstemmed The completeness of the left atrial appendage amputation during routine cardiac surgery
title_short The completeness of the left atrial appendage amputation during routine cardiac surgery
title_sort completeness of the left atrial appendage amputation during routine cardiac surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283164/
https://www.ncbi.nlm.nih.gov/pubmed/37340354
http://dx.doi.org/10.1186/s12872-023-03330-8
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