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Traumatic cardiac arrest – a nationwide Danish study
BACKGROUND: Cardiac arrest following trauma is a leading cause of death, mandating urgent treatment. This study aimed to investigate and compare the incidence, prognostic factors, and survival between patients suffering from traumatic cardiac arrest (TCA) and non-traumatic cardiac arrest (non-TCA)....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283219/ https://www.ncbi.nlm.nih.gov/pubmed/37340347 http://dx.doi.org/10.1186/s12873-023-00839-1 |
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author | Wolthers, Signe Amalie Jensen, Theo Walther Breindahl, Niklas Milling, Louise Blomberg, Stig Nikolaj Andersen, Lars Bredevang Mikkelsen, Søren Torp-Pedersen, Christian Christensen, Helle Collatz |
author_facet | Wolthers, Signe Amalie Jensen, Theo Walther Breindahl, Niklas Milling, Louise Blomberg, Stig Nikolaj Andersen, Lars Bredevang Mikkelsen, Søren Torp-Pedersen, Christian Christensen, Helle Collatz |
author_sort | Wolthers, Signe Amalie |
collection | PubMed |
description | BACKGROUND: Cardiac arrest following trauma is a leading cause of death, mandating urgent treatment. This study aimed to investigate and compare the incidence, prognostic factors, and survival between patients suffering from traumatic cardiac arrest (TCA) and non-traumatic cardiac arrest (non-TCA). METHODS: This cohort study included all patients suffering from out-of-hospital cardiac arrest in Denmark between 2016 and 2021. TCAs were identified in the prehospital medical record and linked to the out-of-hospital cardiac arrest registry. Descriptive and multivariable analyses were performed with 30-day survival as the primary outcome. RESULTS: A total of 30,215 patients with out-of-hospital cardiac arrests were included. Among those, 984 (3.3%) were TCA. TCA patients were younger and predominantly male (77.5% vs 63.6%, p = < 0.01) compared to non-TCA patients. Return of spontaneous circulation occurred in 27.3% of cases vs 32.3% in non-TCA patients, p < 0.01, and 30-day survival was 7.3% vs 14.2%, p < 0.01. An initial shockable rhythm was associated with increased survival (aOR = 11.45, 95% CI [6.24 – 21.24] in TCA patients. When comparing TCA with non-TCA other trauma and penetrating trauma were associated with lower survival (aOR: 0.2, 95% CI [0.02–0.54] and aOR: 0.1, 95% CI [0.03 – 0.31], respectively. Non-TCA was associated with an aOR: 3.47, 95% CI [2.53 – 4,91]. CONCLUSION: Survival from TCA is lower than in non-TCA. TCA has different predictors of outcome compared to non-TCA, illustrating the differences regarding the aetiologies of cardiac arrest. Presenting with an initial shockable cardiac rhythm might be associated with a favourable outcome in TCA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12873-023-00839-1. |
format | Online Article Text |
id | pubmed-10283219 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-102832192023-06-22 Traumatic cardiac arrest – a nationwide Danish study Wolthers, Signe Amalie Jensen, Theo Walther Breindahl, Niklas Milling, Louise Blomberg, Stig Nikolaj Andersen, Lars Bredevang Mikkelsen, Søren Torp-Pedersen, Christian Christensen, Helle Collatz BMC Emerg Med Research BACKGROUND: Cardiac arrest following trauma is a leading cause of death, mandating urgent treatment. This study aimed to investigate and compare the incidence, prognostic factors, and survival between patients suffering from traumatic cardiac arrest (TCA) and non-traumatic cardiac arrest (non-TCA). METHODS: This cohort study included all patients suffering from out-of-hospital cardiac arrest in Denmark between 2016 and 2021. TCAs were identified in the prehospital medical record and linked to the out-of-hospital cardiac arrest registry. Descriptive and multivariable analyses were performed with 30-day survival as the primary outcome. RESULTS: A total of 30,215 patients with out-of-hospital cardiac arrests were included. Among those, 984 (3.3%) were TCA. TCA patients were younger and predominantly male (77.5% vs 63.6%, p = < 0.01) compared to non-TCA patients. Return of spontaneous circulation occurred in 27.3% of cases vs 32.3% in non-TCA patients, p < 0.01, and 30-day survival was 7.3% vs 14.2%, p < 0.01. An initial shockable rhythm was associated with increased survival (aOR = 11.45, 95% CI [6.24 – 21.24] in TCA patients. When comparing TCA with non-TCA other trauma and penetrating trauma were associated with lower survival (aOR: 0.2, 95% CI [0.02–0.54] and aOR: 0.1, 95% CI [0.03 – 0.31], respectively. Non-TCA was associated with an aOR: 3.47, 95% CI [2.53 – 4,91]. CONCLUSION: Survival from TCA is lower than in non-TCA. TCA has different predictors of outcome compared to non-TCA, illustrating the differences regarding the aetiologies of cardiac arrest. Presenting with an initial shockable cardiac rhythm might be associated with a favourable outcome in TCA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12873-023-00839-1. BioMed Central 2023-06-20 /pmc/articles/PMC10283219/ /pubmed/37340347 http://dx.doi.org/10.1186/s12873-023-00839-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Wolthers, Signe Amalie Jensen, Theo Walther Breindahl, Niklas Milling, Louise Blomberg, Stig Nikolaj Andersen, Lars Bredevang Mikkelsen, Søren Torp-Pedersen, Christian Christensen, Helle Collatz Traumatic cardiac arrest – a nationwide Danish study |
title | Traumatic cardiac arrest – a nationwide Danish study |
title_full | Traumatic cardiac arrest – a nationwide Danish study |
title_fullStr | Traumatic cardiac arrest – a nationwide Danish study |
title_full_unstemmed | Traumatic cardiac arrest – a nationwide Danish study |
title_short | Traumatic cardiac arrest – a nationwide Danish study |
title_sort | traumatic cardiac arrest – a nationwide danish study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283219/ https://www.ncbi.nlm.nih.gov/pubmed/37340347 http://dx.doi.org/10.1186/s12873-023-00839-1 |
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