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Traumatic cardiac arrest – a nationwide Danish study

BACKGROUND: Cardiac arrest following trauma is a leading cause of death, mandating urgent treatment. This study aimed to investigate and compare the incidence, prognostic factors, and survival between patients suffering from traumatic cardiac arrest (TCA) and non-traumatic cardiac arrest (non-TCA)....

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Autores principales: Wolthers, Signe Amalie, Jensen, Theo Walther, Breindahl, Niklas, Milling, Louise, Blomberg, Stig Nikolaj, Andersen, Lars Bredevang, Mikkelsen, Søren, Torp-Pedersen, Christian, Christensen, Helle Collatz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283219/
https://www.ncbi.nlm.nih.gov/pubmed/37340347
http://dx.doi.org/10.1186/s12873-023-00839-1
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author Wolthers, Signe Amalie
Jensen, Theo Walther
Breindahl, Niklas
Milling, Louise
Blomberg, Stig Nikolaj
Andersen, Lars Bredevang
Mikkelsen, Søren
Torp-Pedersen, Christian
Christensen, Helle Collatz
author_facet Wolthers, Signe Amalie
Jensen, Theo Walther
Breindahl, Niklas
Milling, Louise
Blomberg, Stig Nikolaj
Andersen, Lars Bredevang
Mikkelsen, Søren
Torp-Pedersen, Christian
Christensen, Helle Collatz
author_sort Wolthers, Signe Amalie
collection PubMed
description BACKGROUND: Cardiac arrest following trauma is a leading cause of death, mandating urgent treatment. This study aimed to investigate and compare the incidence, prognostic factors, and survival between patients suffering from traumatic cardiac arrest (TCA) and non-traumatic cardiac arrest (non-TCA). METHODS: This cohort study included all patients suffering from out-of-hospital cardiac arrest in Denmark between 2016 and 2021. TCAs were identified in the prehospital medical record and linked to the out-of-hospital cardiac arrest registry. Descriptive and multivariable analyses were performed with 30-day survival as the primary outcome. RESULTS: A total of 30,215 patients with out-of-hospital cardiac arrests were included. Among those, 984 (3.3%) were TCA. TCA patients were younger and predominantly male (77.5% vs 63.6%, p =  < 0.01) compared to non-TCA patients. Return of spontaneous circulation occurred in 27.3% of cases vs 32.3% in non-TCA patients, p < 0.01, and 30-day survival was 7.3% vs 14.2%, p < 0.01. An initial shockable rhythm was associated with increased survival (aOR = 11.45, 95% CI [6.24 – 21.24] in TCA patients. When comparing TCA with non-TCA other trauma and penetrating trauma were associated with lower survival (aOR: 0.2, 95% CI [0.02–0.54] and aOR: 0.1, 95% CI [0.03 – 0.31], respectively. Non-TCA was associated with an aOR: 3.47, 95% CI [2.53 – 4,91]. CONCLUSION: Survival from TCA is lower than in non-TCA. TCA has different predictors of outcome compared to non-TCA, illustrating the differences regarding the aetiologies of cardiac arrest. Presenting with an initial shockable cardiac rhythm might be associated with a favourable outcome in TCA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12873-023-00839-1.
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spelling pubmed-102832192023-06-22 Traumatic cardiac arrest – a nationwide Danish study Wolthers, Signe Amalie Jensen, Theo Walther Breindahl, Niklas Milling, Louise Blomberg, Stig Nikolaj Andersen, Lars Bredevang Mikkelsen, Søren Torp-Pedersen, Christian Christensen, Helle Collatz BMC Emerg Med Research BACKGROUND: Cardiac arrest following trauma is a leading cause of death, mandating urgent treatment. This study aimed to investigate and compare the incidence, prognostic factors, and survival between patients suffering from traumatic cardiac arrest (TCA) and non-traumatic cardiac arrest (non-TCA). METHODS: This cohort study included all patients suffering from out-of-hospital cardiac arrest in Denmark between 2016 and 2021. TCAs were identified in the prehospital medical record and linked to the out-of-hospital cardiac arrest registry. Descriptive and multivariable analyses were performed with 30-day survival as the primary outcome. RESULTS: A total of 30,215 patients with out-of-hospital cardiac arrests were included. Among those, 984 (3.3%) were TCA. TCA patients were younger and predominantly male (77.5% vs 63.6%, p =  < 0.01) compared to non-TCA patients. Return of spontaneous circulation occurred in 27.3% of cases vs 32.3% in non-TCA patients, p < 0.01, and 30-day survival was 7.3% vs 14.2%, p < 0.01. An initial shockable rhythm was associated with increased survival (aOR = 11.45, 95% CI [6.24 – 21.24] in TCA patients. When comparing TCA with non-TCA other trauma and penetrating trauma were associated with lower survival (aOR: 0.2, 95% CI [0.02–0.54] and aOR: 0.1, 95% CI [0.03 – 0.31], respectively. Non-TCA was associated with an aOR: 3.47, 95% CI [2.53 – 4,91]. CONCLUSION: Survival from TCA is lower than in non-TCA. TCA has different predictors of outcome compared to non-TCA, illustrating the differences regarding the aetiologies of cardiac arrest. Presenting with an initial shockable cardiac rhythm might be associated with a favourable outcome in TCA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12873-023-00839-1. BioMed Central 2023-06-20 /pmc/articles/PMC10283219/ /pubmed/37340347 http://dx.doi.org/10.1186/s12873-023-00839-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Wolthers, Signe Amalie
Jensen, Theo Walther
Breindahl, Niklas
Milling, Louise
Blomberg, Stig Nikolaj
Andersen, Lars Bredevang
Mikkelsen, Søren
Torp-Pedersen, Christian
Christensen, Helle Collatz
Traumatic cardiac arrest – a nationwide Danish study
title Traumatic cardiac arrest – a nationwide Danish study
title_full Traumatic cardiac arrest – a nationwide Danish study
title_fullStr Traumatic cardiac arrest – a nationwide Danish study
title_full_unstemmed Traumatic cardiac arrest – a nationwide Danish study
title_short Traumatic cardiac arrest – a nationwide Danish study
title_sort traumatic cardiac arrest – a nationwide danish study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283219/
https://www.ncbi.nlm.nih.gov/pubmed/37340347
http://dx.doi.org/10.1186/s12873-023-00839-1
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