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Pathological ultrastructural alterations of myelinated axons in normal appearing white matter in progressive multiple sclerosis

Multiple sclerosis (MS) pathophysiology includes inflammation, demyelination and neurodegeneration, but the exact mechanisms of disease initiation and progression are unknown. A major feature of lesions is lack of myelin, which increases axonal energy demand and requires adaptation in number and siz...

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Detalles Bibliográficos
Autores principales:	Oost, Wendy, Huitema, Allard J., Kats, Kim, Giepmans, Ben N. G., Kooistra, Susanne M., Eggen, Bart J. L., Baron, Wia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283269/ https://www.ncbi.nlm.nih.gov/pubmed/37340488 http://dx.doi.org/10.1186/s40478-023-01598-7

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