Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy

Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons and inflammatory responses. Whereas microglia are very competent phagocytes under physiological conditions, we report their dysfunction in mouse and preclinical monkey models of stroke (macaques and marmosets) by...

Descripción completa

Detalles Bibliográficos
Autores principales: Beccari, Sol, Sierra-Torre, Virginia, Valero, Jorge, Pereira-Iglesias, Marta, García-Zaballa, Mikel, Soria, Federico N., De Las Heras-Garcia, Laura, Carretero-Guillen, Alejandro, Capetillo-Zarate, Estibaliz, Domercq, Maria, Huguet, Paloma R., Ramonet, David, Osman, Ahmed, Han, Wei, Dominguez, Cecilia, Faust, Travis E., Touzani, Omar, Pampliega, Olatz, Boya, Patricia, Schafer, Dorothy, Mariño, Guillermo, Canet-Soulas, Emmanuelle, Blomgren, Klas, Plaza-Zabala, Ainhoa, Sierra, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283420/
https://www.ncbi.nlm.nih.gov/pubmed/36622892
http://dx.doi.org/10.1080/15548627.2023.2165313

Ejemplares similares

Ejemplares similares