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Copper-dependent autophagic degradation of GPX4 drives ferroptosis

Ferroptosis is a type of iron-dependent regulated cell death characterized by unrestricted lipid peroxidation and membrane damage. Although GPX4 (glutathione peroxidase 4) plays a master role in blocking ferroptosis by eliminating phospholipid hydroperoxides, the regulation of GPX4 remains poorly un...

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Detalles Bibliográficos
Autores principales:	Xue, Qian, Yan, Ding, Chen, Xi, Li, Xiaofen, Kang, Rui, Klionsky, Daniel J., Kroemer, Guido, Chen, Xin, Tang, Daolin, Liu, Jinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283421/ https://www.ncbi.nlm.nih.gov/pubmed/36622894 http://dx.doi.org/10.1080/15548627.2023.2165323

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