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Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis

Dysfunction of the endosomal sorting complex required for transport (ESCRT) has been linked to frontotemporal dementia (FTD) due in part to the accumulation of unsealed autophagosomes. However, the mechanisms of ESCRT-mediated membrane closure events on phagophores remain largely unknown. In this st...

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Detalles Bibliográficos
Autores principales: Jun, Yong-Woo, Lee, Soojin, Ban, Byung-Kwan, Lee, Jin-A, Gao, Fen-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283425/
https://www.ncbi.nlm.nih.gov/pubmed/36849436
http://dx.doi.org/10.1080/15548627.2023.2169309