Dynamic frustrated charge hotspots created by charge density modulation sequester globular proteins into complex coacervates

This study presents a simple strategy for the sequestration of globular proteins as clients into synthetic polypeptide-based complex coacervates as a scaffold, thereby recapitulating the scaffold-client interaction found in biological condensates. Considering the low net charges of scaffold proteins...

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Detalles Bibliográficos
Autores principales: K C, Biplab, Nii, Teruki, Mori, Takeshi, Katayama, Yoshiki, Akihiro Kishimura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283495/
https://www.ncbi.nlm.nih.gov/pubmed/37350836
http://dx.doi.org/10.1039/d3sc00993a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283495/
https://www.ncbi.nlm.nih.gov/pubmed/37350836
http://dx.doi.org/10.1039/d3sc00993a

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