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Dynamic frustrated charge hotspots created by charge density modulation sequester globular proteins into complex coacervates
This study presents a simple strategy for the sequestration of globular proteins as clients into synthetic polypeptide-based complex coacervates as a scaffold, thereby recapitulating the scaffold-client interaction found in biological condensates. Considering the low net charges of scaffold proteins...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283495/ https://www.ncbi.nlm.nih.gov/pubmed/37350836 http://dx.doi.org/10.1039/d3sc00993a |