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Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis

PURPOSE: The aim of this study was to investigate the effect of dexmedetomidine (Dex) on inflammation and organ injury in sepsis, as well as the potential relationship between Dex and nuclear receptor 77 (Nur77). METHODS: We investigated the effects of dexmedetomidine on lipopolysaccharide (LPS)‐ind...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Huang, Yun, Gong, Chenchen, Tang, Yan, Xiong, Jie, Wang, Difen, Liu, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283499/
https://www.ncbi.nlm.nih.gov/pubmed/37382273
http://dx.doi.org/10.1002/iid3.883