Cargando…

Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment

The development of novel therapies for brain metastases is an unmet need. Brain metastases may have unique molecular features that could be explored as therapeutic targets. A better understanding of the drug sensitivity of live cells coupled to molecular analyses will lead to a rational prioritizati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morikawa, Aki, Li, Jinju, Ulintz, Peter, Cheng, Xu, Apfel, Athena, Robinson, Dan, Hopkins, Alex, Kumar-Sinha, Chandan, Wu, Yi-Mi, Serhan, Habib, Verbal, Kait, Thomas, Dafydd, Hayes, Daniel F., Chinnaiyan, Arul M., Baladandayuthapani, Veerabhadran, Heth, Jason, Soellner, Matthew B., Merajver, Sofia D., Merrill, Nathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284082/ https://www.ncbi.nlm.nih.gov/pubmed/37377606 http://dx.doi.org/10.1158/2767-9764.CRC-22-0492

Ejemplares similares

IMPACT the Brain: A Team-Based Approach to Management of Metastatic Breast Cancer With CNS Metastases
por: Fleege, Nicole M. Grogan, et al.
Publicado: (2023)

OTHR-13. IMPACT the brain: improving metastatic breast cancer patient access to coordinated treatment
por: Grogan, Nicole, et al.
Publicado: (2021)

Landscape of gene fusions in epithelial cancers: seq and ye shall find
por: Kumar-Sinha, Chandan, et al.
Publicado: (2015)

Bayesian Disease Classification Using Copy Number Data
por: Guha, Subharup, et al.
Publicado: (2014)

BaySyn: Bayesian Evidence Synthesis for Multi-system Multiomic Integration
por: Bhattacharyya, Rupam, et al.
Publicado: (2023)

Integrative Bayesian Network Analysis of Genomic Data
por: Ni, Yang, et al.
Publicado: (2014)

Bayesian Covariate-Dependent Gaussian Graphical Models with Varying Structure
por: Ni, Yang, et al.
Publicado: (2022)

Classification, Predictive Modelling, and Statistical Analysis of Cancer Data (A)
por: Jiang, Hongmei, et al.
Publicado: (2014)

Prognostic Gene Signature Identification Using Causal Structure Learning: Applications in Kidney Cancer
por: Ha, Min Jin, et al.
Publicado: (2015)

Bayesian graphical models for modern biological applications
por: Ni, Yang, et al.
Publicado: (2021)

RNA-Seq Accurately Identifies Cancer Biomarker Signatures to Distinguish Tissue of Origin()
por: Wei, Iris H., et al.
Publicado: (2014)

Urothelial Cancer With Occult Bone Marrow Metastases and Isolated Thrombocytopenia
por: Alva, Ajjai, et al.
Publicado: (2015)

Integrating multi-platform genomic data using hierarchical Bayesian relevance vector machines
por: Srivastava, Sanvesh, et al.
Publicado: (2013)

Integrative network-based Bayesian analysis of diverse genomics data
por: Wang, Wenting, et al.
Publicado: (2013)

SPARTIN: a Bayesian method for the quantification and characterization of cell type interactions in spatial pathology data
por: Osher, Nathaniel, et al.
Publicado: (2023)

DIMPLE: AN R PACKAGE TO QUANTIFY, VISUALIZE, AND MODEL SPATIAL CELLULAR INTERACTIONS FROM MULTIPLEX IMAGING WITH DISTANCE MATRICES
por: MASOTTI, MARIA, et al.
Publicado: (2023)

Bayesian Joint Selection of Genes and Pathways: Applications in Multiple Myeloma Genomics
por: Zhang, Lin, et al.
Publicado: (2014)

Tree-based Methods for Characterizing Tumor Density Heterogeneity
por: Shoemaker, Katherine, et al.
Publicado: (2018)

iDINGO—integrative differential network analysis in genomics with Shiny application
por: Class, Caleb A, et al.
Publicado: (2018)

Network-Based Matching of Patients and Targeted Therapies for Precision Oncology
por: Liu, Qingzhi, et al.
Publicado: (2020)

Impact of between-tissue differences on pan-cancer predictions of drug sensitivity
por: Lloyd, John P., et al.
Publicado: (2021)

Identification of Novel PGR-NR4A3 Fusion in Extraskeletal Myxoid Chondrosarcoma and Resultant Patient Benefit From Tamoxifen Therapy
por: Wilbur, H. Catherine, et al.
Publicado: (2022)

Bayesian methods for expression-based integration of various types of genomics data
por: Jennings, Elizabeth M, et al.
Publicado: (2013)

Bayesian variable selection with graphical structure learning: Applications in integrative genomics
por: Kundu, Suprateek, et al.
Publicado: (2018)

Personalized Network Modeling of the Pan-Cancer Patient and Cell Line Interactome
por: Bhattacharyya, Rupam, et al.
Publicado: (2020)

MEK is a promising target in the basal subtype of bladder cancer
por: Merrill, Nathan M., et al.
Publicado: (2020)

iBAG: integrative Bayesian analysis of high-dimensional multiplatform genomics data
por: Wang, Wenting, et al.
Publicado: (2013)

Double-Negative Prostate Cancer Masquerading as a Squamous Cancer of Unknown Primary: A Clinicopathologic and Genomic Sequencing-Based Case Study
por: Cackowski, Frank C., et al.
Publicado: (2020)

Personalized Integrated Network Modeling of the Cancer Proteome Atlas
por: Ha, Min Jin, et al.
Publicado: (2018)

OTHR-12. DRIVING RECOMMENDATIONS IN PATIENTS WITH NEWLY DIAGNOSED BREAST CANCER BRAIN METASTASES
por: Swartz, Leigh, et al.
Publicado: (2019)

Heterogeneity at the invasion front of triple negative breast cancer cells
por: Aw Yong, Koh Meng, et al.
Publicado: (2020)

RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers
por: Abraham, Hannah G., et al.
Publicado: (2021)

Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma
por: Wang, Hua, et al.
Publicado: (2017)

Transcriptome Sequencing to Detect Gene Fusions in Cancer
por: Maher, Christopher A., et al.
Publicado: (2009)

A Comparison of Single Molecule and Amplification Based Sequencing of Cancer Transcriptomes
por: Sam, Lee T., et al.
Publicado: (2011)

Classification and Selection of Biomarkers in Genomic Data Using LASSO
por: Ghosh, Debashis, et al.
Publicado: (2005)

Radiomic analysis in prediction of Human Papilloma Virus status
por: Yu, Kaixian, et al.
Publicado: (2017)

PubMed QUEST: The PubMed Query Search Tool. An informatics tool to aid cancer centers and cancer investigators in searching the PubMed databases
por: Hanauer, David A., et al.
Publicado: (2007)

BETting on a new prostate cancer treatment
por: Asangani, Irfan A, et al.
Publicado: (2014)

Role of multiresolution vulnerability indices in COVID-19 spread in India: a Bayesian model-based analysis
por: Bhattacharyya, Rupam, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fl7fcut8fgk91fdsgp7ttrhv2k