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Efficient enzymatic synthesis of chiral 2,3-dihydro-1,4-benzodioxane motif using engineered Candida antarctica lipase B

Chiral motifs of 2,3-dihydro-1,4 benzodioxane are extensively utilized in diverse medicinal substances and bioactive natural compounds, exhibiting significant biological activities. Notable examples of such therapeutic agents include prosympal, dibozane, piperoxan, and doxazosin. In this work, using...

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Detalles Bibliográficos
Autores principales:	Wu, Zhiyun, Shi, Weifeng, Jin, Ming, Zhou, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284148/ https://www.ncbi.nlm.nih.gov/pubmed/37350861 http://dx.doi.org/10.1039/d3ra02623j

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