Cargando…
Mslar: Microbial synthetic lethal and rescue database
Synthetic lethality (SL) occurs when mutations in two genes together lead to cell or organism death, while a single mutation in either gene does not have a significant impact. This concept can also be extended to three or more genes for SL. Computational and experimental methods have been developed...
Autores principales: | Zhu, Sen-Bin, Jiang, Qian-Hu, Chen, Zhi-Guo, Zhou, Xiang, Jin, Yan-ting, Deng, Zixin, Guo, Feng-Biao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284384/ https://www.ncbi.nlm.nih.gov/pubmed/37289843 http://dx.doi.org/10.1371/journal.pcbi.1011218 |
Ejemplares similares
-
DNA repair and synthetic lethality
por: Guo, Gong-she, et al.
Publicado: (2011) -
IFIM: a database of integrated fitness information for microbial genes
por: Wei, Wen, et al.
Publicado: (2014) -
Computational methods, databases and tools for synthetic lethality prediction
por: Wang, Jing, et al.
Publicado: (2022) -
SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets
por: Guo, Jing, et al.
Publicado: (2016) -
SLOAD: a comprehensive database of cancer-specific synthetic lethal interactions for precision cancer therapy via multi-omics analysis
por: Guo, Li, et al.
Publicado: (2022)