Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses

Epithelial immune responses govern tissue homeostasis and offer drug targets against maladaptation. Here, we report a framework to generate drug discovery–ready reporters of cellular responses to viral infection. We reverse-engineered epithelial cell responses to SARS-CoV-2, the viral agent fueling...

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Detalles Bibliográficos
Autores principales: Jiang, Ben, Schmitt, Matthias Jürgen, Rand, Ulfert, Company, Carlos, Dramaretska, Yuliia, Grossmann, Melanie, Serresi, Michela, Čičin-Šain, Luka, Gargiulo, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284557/
https://www.ncbi.nlm.nih.gov/pubmed/37343108
http://dx.doi.org/10.1126/sciadv.adf4975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284557/
https://www.ncbi.nlm.nih.gov/pubmed/37343108
http://dx.doi.org/10.1126/sciadv.adf4975

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