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Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand

Mitochondrial ATP production in ventricular cardiomyocytes must be continually adjusted to rapidly replenish the ATP consumed by the working heart. Two systems are known to be critical in this regulation: mitochondrial matrix Ca(2+) ([Ca(2+)](m)) and blood flow that is tuned by local cardiomyocyte m...

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Detalles Bibliográficos
Autores principales: Greiser, Maura, Karbowski, Mariusz, Kaplan, Aaron David, Coleman, Andrew Kyle, Verhoeven, Nicolas, Mannella, Carmen A, Lederer, W Jonathan, Boyman, Liron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284600/
https://www.ncbi.nlm.nih.gov/pubmed/37272417
http://dx.doi.org/10.7554/eLife.84204

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